WebNov 2, 2024 · By analyzing a scRNA sequence data set of tumor-associated myeloid cells, we identified two TIM4 + FOLR2 + clusters coherent with CA TIM4 + MΦ and TLS TIM4 + MΦ. We defined specific gene signatures for each subset and found that the CA TIM4 + MΦ signature was associated with worse patient survival. WebApr 12, 2024 · Interestingly, e&ysMacs showed similar transcriptomic features to HBCs, with high expression of FOLR2, CD14, CD44, ... The UMAP Projection analysis was performed to compare the cell subtypes of decidual NK cells and decidual macrophages between human and macaque with the "MapQuery" function of Seurat v4.0.0. 69 Briefly, ...
FOLR2 + Macrophages Are Associated with T-cell Infiltration and ...
WebMar 30, 2024 · Placental macrophages, termed Hofbauer cells (HBC), first appear at ~18 days post conception 1. They rapidly proliferate and are highly abundant within first-trimester placental villi, the... WebDec 14, 2009 · We report that folate receptor β (FRβ), encoded by the FOLR2 gene, is a marker for macrophages generated in the presence of M-CSF (M2), but not GM-CSF (M1), and whose expression correlates … top rated canned dog foods
Tissue-resident FOLR2+ macrophages associate with …
WebMay 14, 2015 · Since FOLR2 has been described to be expressed by macrophages, we sought to employ duplex RNAscope to investigate whether FOLR2 co-expressed with known macrophage markers CD11b and/or CD68. Using probes for CD11b and CD68 resulted in two apparently distinct populations of macrophages with some cells expressing both … WebApr 12, 2024 · Here, we identify a discrete population of FOLR2 + tumor-associated macrophages positively correlating with patient survival in breast cancer. FOLR2 + … WebJan 7, 2024 · The first macrophage subset (MF1) in each human organ expressed LYVE1, FOLR2, and several recurring markers (MRC1, F13A1, and CD163), which comprised part of the core transcriptional signature … top rated canned wet dog foods