Lutheran blood group glycoprotein
WebApr 1, 2006 · The Lutheran blood group system, which comprises one of the largest families of human red blood cell (RBC) antigens, resides on two immunoglobulin superfamily (IgSF) proteins: Lutheran and basal cell adhesion molecule (B‐CAM). WebDec 15, 2008 · The Lutheran (Lu) and Lu (v13) blood group glycoproteins function as receptors for extracellular matrix laminins. Lu and Lu (v13) are linked to the erythrocyte cytoskeleton through a direct interaction with spectrin. However, neither the molecular basis of the interaction nor its functional consequences have previously been delineated.
Lutheran blood group glycoprotein
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WebLaminin alpha-5 receptor. May mediate intracellular signaling. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal … WebOn RBCs, Lutheran glycoprotein may be involved in the adherence of RBCs to vascular endothelial cells and in the vaso-occlusion that is characteristic of sickle cell disease. 51 …
WebFind the nearest Red Cross blood, platelet or plasma donation center. Make a difference in someone's life, give the gift of life. Find a Drive Sign In. Give Blood. Find a Drive. ZIP or … WebThe Lutheran blood group glycoprotein (Lu), an Ig superfamily (IgSF) transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM). Lu/B-CAM is a specific receptor for laminin α5,...
WebJan 1, 2001 · The Lutheran blood group is composed of a complex set of antigens expressed on 2 integral membrane glycoprotein isoforms of 85 and 78 kd.1,2 The … WebPrimePCR™ Template for Probe Assay: BCAM, Human Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.
WebDec 7, 2007 · Many of these proteins express blood group activity. The functions of some of these proteins are known; in others their function can only be surmised from the protein structure or from limited experimental evidence. ... Binds chemokines, possibly for removal from peripheral blood. Lutheran glycoprotein (CD329) LU: 005 Lutheran: T1, IgSF (IgV-V ...
WebABSTRACT Glycoproteins expressing the Lutheran blood group antigens were isolated from human erythrocyte membranes and from human fetal liver. Amino acid sequence … columbus clerks officeWebMar 29, 2024 · This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. columbus civic center disney on iceWebAug 12, 2011 · The Lutheran blood group glycoprotein (Lu), an Ig superfamily (IgSF) transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM). Lu/B … dr toby yalthoWebThe Lutheran glycoprotein: a multifunctional adhesion receptor The Lutheran blood group system, which comprises one of the largest families of human red blood cell (RBC) … dr toby wilsonWebhe Lutheran blood group system (BGS) consists of a large number of antigens, 24 being recognised by the International Society of Blood Transfusion at the time of writing, and is also of interest in terms of the various backgrounds to the (apparent) Lu(a-b-) phenotypes. The Lutheran BGS is also incorrectly named, as will be explained shortly. dr toby weaver salisbury mdWebJun 6, 1995 · The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver. S F Parsons, G Mallinson, C H Holmes, +6, J M Houlihan, K L Simpson, W J Mawby, N K Spurr, D Warne, A N Barclay, and D J Anstee-6 Authors Info & … dr toby watson sheboyganWebJan 28, 2013 · The Lutheran glycoproteins (CD239) are a pair of isoforms that belong to the immunoglobulin superfamily. Their function is unknown, but they bind the extracellular … dr toby taylor utica ny address