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OSMR gene effect on the pathogenesis of chronic …
WebOSM and OSMR are highly expressed in inflammatory bowel disease intestinal mucosa compared to control mucosa. Intestinal stromal cells express abundant OSMR. OSM:OSMR interactions are able to induce EMT, increased cancer stem cell-like properties and enhanced lung colonisation in SCC cells WebOncostatin M receptor (OSMR), a growth regulating cytokine, is known to be overexpressed in multiple cancers and lead to a more aggressive phenotype (4—6). This makes the cell surface receptor a viable therapeutic target. Recently, there has been an increase in the use of radiolabeled ligands in pearson lift 2.0
Overexpression of oncostatin M receptor regulates local immune …
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