WebMar 11, 2004 · The C-terminal regions of TSPs are also involved in human disease. Two related autosomal dominant skeletal disorders, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED), are linked to mutations in COMP ( Briggs et al, 1995; Hecht et al, 1995 ). WebActivation of the P2X7 receptor results in the opening of a large pore that plays a role in immune responses, apoptosis, and many other physiological and pathological processes. Here, we investigated the role of conserved and unique residues in the extracellular vestibule connecting the agonist-binding domain with the transmembrane domain of rat P2X7 …
Tb10.26.0280 - PSP1 C-terminal domain-containing …
WebPSP1_C, PS51411; PSP1 C-terminal domain profile (MATRIX) Sequences in UniProtKB/Swiss-Prot known to belong to this class: 5. detected by PS51411: 5 (true … WebNOPS domain, including C-terminal coiled-coil region, in paraspeckle protein component 1 (PSPC1) and similar proteins The family contains a DBHS domain (for Drosophila … sewn with love by eak
PSP1 - PFAM28P - GREMLIN Contacts
WebApr 27, 2024 · Here we considered peptide-based approach as an attractive alternative strategy to direct the antibody response against a neutralizing site of gp350. The N-terminus fragment gp350 1-425 retains the complete binding activity with the receptor CR2. Therefore, peptides localized to this region are ideal candidates for a rational design of EBV ... WebMay 14, 2024 · sequence is highly conserved. This protein contains two structural domains: the N-terminal domain, that acts as a putative RNA binding domain, and a C-terminal domain, which acts as a dimerization domain [Tilocca et al. 2024]. T cell- responses against S and N proteins have been shown to be the most immunogenic and long lasting in SARS- WebJan 1, 2024 · The drp1 C-terminus truncated mutants drp1C1Δ, drp1C2Δ, as well as drp1M218I mutant cells, exhibit mild sensitivity against MMS and UV exposure at the permissive temperature ( Fig. 2 A and B) suggesting the involvement of Drp1 during recovery from DNA damaging agent. sewnwildoaks.blogspot.com