Tmem63a是什么
WebOur TMEM63A polyclonal antibodies are developed in Rabbit. Find the TMEM63A antibody that fits your needs. Choose from 1 of 4 TMEM63A antibodies, which have been validated in experiments with 4 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Transmembrane protein 63A is a protein that in humans is encoded by the TMEM63A gene. The mature human protein is approximately 92.1 kilodaltons (kDa), with a relatively high conservation of mass in orthologs. The protein contains eleven transmembrane domains and is inserted into the membrane of … See more Overview TMEM63A is located on the negative DNA strand of chromosome 1 at location 1q42.12, spanning base pairs 226,033,237 to 226,070,069. Aliases include KIAA0489 and KIAA0792. The … See more Properties and characteristics The mature form of the human TMEM63A protein has 807 amino acid residues with an isoelectric point of 6.925. This is fairly conserved across … See more • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): … See more Paralogs TMEM63A has two paralogs: TMEM63B, which is located at 6p21.1, and TMEM63C, which is located at C14orf171. Alignment between them shows that TMEM63C is more closely related to TMEM63B than TMEM63A. A BLAST … See more
Tmem63a是什么
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WebFeb 1, 2024 · We found a de novo variant in TMEM63A (NM_014698.3:c.1658G>T, p.(Gly553Val)), which was validated by Sanger sequencing (Fig. 2 A). This variant … WebThis is a rabbit polyclonal antibody against TMEM63A and was validated on Western blot. Theoretical MW. 89 kDa. Disclaimer note: The observed molecular weight of the protein …
WebHuman diseases caused by Tmem63a mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER. Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes. Human diseases associated with … WebIDG-HEK293T-TMEM63A-V5-OE. Selection: Blasticidin to a final concentration of 10μg/m. Organism: Homo sapiens, human. Description: This cell line stably expresses dark ion channel in frame with V5 tag on the C-terminus. The ion channel construct is randomly integrated in the genome using lentiviral transduction. This cell line also expresses ...
WebNov 8, 2016 · Spinal cord involvement and paroxysmal events in "Infantile Onset Transient Hypomyelination" due to TMEM63A mutation. The N- and C-terminal carbohydrate recognition domains of Haemonchus contortus galectin bind to distinct receptors of goat PBMC and contribute differently to its immunomodulatory functions in host-parasite … WebNov 1, 2024 · Our results suggest that OSCA/TMEM63 proteins are the largest family of MA ion channels identified, and are conserved across eukaryotes. Our findings will enable …
WebApr 9, 2015 · Our results show that TMEM63A is a binding partner of Hco-gal-m/f, and involved in the immune responses of host PBMCs induced by Hco-gal-m for the first time. Hco-gal-m and -f were two isoforms of galectin cloned from male and female Haemonchus contortus, respectively, and it was demonstrated that recombinant Hco-gal-m and -f could …
WebCRISPR/Cas9 KO Plasmids consists of TMEM63A-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA. Target-specific CRISPR Plasmids for both gene knockout and activation are available. highlights napoli fiorentinaWebMar 21, 2024 · TMEM63A (Transmembrane Protein 63A) is a Protein Coding gene. Diseases associated with TMEM63A include Leukodystrophy, Hypomyelinating, 19, Transient … highlights napoli mallorcaWebCell ID: IDG-HEK293T-TMEM63A-V5-OE. Selection: Blasticidin to a final concentration of 10μg/m. Organism: Homo sapiens, human. Description: This cell line stably expresses … small portable hooverWebKJ892838 - Synthetic construct Homo sapiens clone ccsbBroadEn_02232 TMEM63A gene, encodes complete protein. AB383993 - Synthetic construct DNA, clone: pF1KSDA0792, Homo sapiens TMEM63A gene for transmembrane protein 63A, complete cds, without stop codon, in Flexi system. AK093860 - Homo sapiens cDNA FLJ36541 fis, clone … small portable hot tubsWebCatalog #. AM16708. Standard 5 nmol. Purification: HPLC In-Vivo Ready Standard. Size: 5 nmol 20 nmol 20 nmol 20 nmol 20 nmol 40 nmol 40 nmol 100 nmol 250 nmol 250 nmol 1 umol 10 umol. Availability: Inventoried. small portable house 16x24WebTransmembrane protein 63A is a protein that in humans is encoded by the TMEM63A gene.[5][6][7] The mature human protein is approximately 92.1 kilodaltons , with a … small portable house plansWebJul 12, 2024 · TMEM63A is a newly-identified mechanosensitive ion channel. 75.6% ± 2.4% of Tmem63a + DRG neurons were IB4 + DRG neurons and 95.7% ± 1.7% of IB4 + DRG … highlights napoli torino